Contents
hPSC-Dopaminergic Progenitors (Day11)
Cat. No. RC01008
Features：Derived from iPSC, can be differentiated into mDAN.
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|
Amount |
Cat. No. |
Storage |
|
hiPSC-mDAP（Day11） |
1×10⁶ |
RC01008 |
Liquid nitrogen |
- Overview
- Citation
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hiPSC-mDAP（RC01008） are high-purity (>90% Lmx1a+/Foxa2+/En1+) dopaminergic progenitors (mDAP) generated from human pluripotent stem cells (hPSC). hPSC-mDAP can be expanded and passaged while retaining the ability to differentiate into mature dopaminergic neurons (mDAN). hiPSC-mDAP is suitable for research on neurodegenerative diseases, drug screening, and studies in cell transplantation in Parkinson's disease models.
hPSC-mDAP morphology
(A-C) The morphology of hPSC-mDAP cultured at day 1, 2, and 4 after cell recovery.
(D-F) The morphology of mDAP differentiated into mDNA at day 1, 9, and 30. Scale bar, 200μm.
hPSC-mDAP specific markers expression
Immunofluorescence staining for LMX1A, FOXA2, and EN1 on hiPSC-mDAP. Scale bar, 200 μm.
hPSC-mDAN specific markers expression and functional analysis
(M-O) Immunofluorescence staining for TH and Nurr1 on differentiated mDAN at day 25. Scale bar, 200 μm.
(P-R) A representative image of electrophysiological recording on individual mDAN at day 33 after cell recovery.
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